Fall 2010 HAABB Meeting: Program Overview
Sailing through a Work-up
Elaine Scott, MT(ASCP)SBB, American Red Cross, MO/IL Region, St. Louis, MO
Elaine presented an interesting case where the Immunohematology Reference Laboratory used "thinking
outside of the box" as a tool for resolving incompatible crossmatches in a patient with multiple alloantibodies.
Implementing a Transfusion Safety Program
Daniel S. Smith, MD, Professor of Transfusion Medicine, Indiana University, Indianapolis, IN
ABO Mystery Theatre: To B or Not To B!
David Baker, MBA, MT(ASCP), Children’s Hospital, St. Louis, MO
Discussed a case of passenger lymphocyte syndrome affecting a patient at SLCH. Reviewed the frequency
and typical outcomes of the syndrome. Passenger Lymphocyte Syndrome refers to the clinical phenomenon
of alloimmune hemolysis resulting from the adoptive transfer of viable lymphocytes from the donor during
solid organ and hematopoietic stem cell transplants. Donor's antibodies can be of ABO or non-ABO origin.
Management strategies include immunosuppression, immune-modulation (IVIG), B-Cell targeting (Rituximab)
and/or exchange transfusion.
“Local Boyd Makes Good”; William Clouser Boyd Blood Groups and Anthropology
Steve Pierce, SBB(ASCP), Retired, Kansas City, MO
Following Ludwig Hirszfeld's report in 1919 that ABO prevalence varied in different populations, blood
groups became widely used in physical anthropology. William Clouser Boyd, from Missouri, was one of the
leading Americans to use blood groups in anthropological investigations. He was the first to type Egyptian
mummies and introduced the use of lectins to Type red blood cells. This historical presentation examined
seroanthropology and Boyd's contributions to blood group serology.
Platelet Additive Solution: How Can Something So Simple Be So Complicated?
Peyton S. Metzel, PhD, Vice President, Scientific Affairs, Fenwal Inc, Lake Zurich, IL
Are You My Mother? In Vitro Fertility Challenges in the Blood Bank
Faith Nilhas, MLS(ASCP), Blood Bank, Lawrence Memorial Hospital, Lawrence, KS
Investigation of ABORh discrepancies between cord bloods of newborns and their mothers is important to
rule out possible mislabeling of specimens and to assure testing is correct to prevent possible D
alloiommunization of Rh Negative women. This case study discussed the discovery that in vitro fertilization
methods may have been used to achieve pregnancy and that sensitive privacy issues can arise as a result of
the Blood Bank needing to resolve ABO discrepancies.
Monoclonal Reagent Case Studies
Christina Barron, MT(ASCP)SBB, American Red Cross, MO/IL Region, St. Louis, MO
Knowing the clones that are used to manufacture your monoclonal reagents can make a big difference in the results you
obtain. Chris presented several examples typing discrepancies that ultimately were resolved by evualting the clones in
the reagents used. A wonderful table was also provided.
Immune-Mediated Coagulopathy Following Topical Hemostat Use
Michael Creer, MD, Professor of Pathology and Laboratory Medicine
St. Louis University School of Medicine, St. Louis, MO
